Zycortal Suspension (Desoxycorticosterone Pivalate) is an injectable for use as replacement therapy in dogs with Addison's Disease. This condition is a mineralocorticoid deficiency in canines with primary hypoadrenocorticism.
What is Zycortal Suspension for Dogs, 25 mg/ml, 4 ml Vial?
It is an injectable for use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s Disease).
Who is Zycortal Suspension for Dogs, 25 mg/ml, 4 ml Vial for?
Dogs
Why use Zycortal Suspension for Dogs, 25 mg/ml, 4 ml Vial?
To treat Addison's Disease
How does Zycortal Suspension for Dogs, 25 mg/ml, 4 ml Vial work?
It increases extracellular fluid volume, blood volume expansion, improves venous return to the heart, and increases cardiac output
Dechra
Desoxycorticosterone Pivalate
How is Zycortal Suspension for Dogs, 25 mg/ml, 4 ml Vial sold?
25 mg/ml, 4 ml vial
What are the side effects of Zycortal Suspension for Dogs, 25 mg/ml, 4 ml Vial?
It has been demonstrated that Desoxycorticosterone Pivalate Injectable Suspension is well tolerated with a low incidence of side effects. In a small percentage of treated dogs, depression, excessive thirst and urination, digestive, skin and coat changes, weakness, and injection site reactions (pain, abscesses) may occur. Some of these effects may resolve with adjustments in dose or interval or concomitant glucocorticoid administration. Do not use in pregnant dogs or in dogs that are suffering from congestive heart disease, severe renal disease, or edema.
What special precautions are there?
Do not use Zycortal Suspension in dogs that have previously had a hypersensitivity reaction to desoxycorticosterone pivalate. CAUTIONS: Any dog presenting with severe hypovolemia, dehydration, pre-renal azotemia and inadequate tissue perfusion (“Addisonian crisis”) must be rehydrated with intravenous fluid (saline) therapy before starting treatment with Zycortal Suspension. Avoid inadvertent intravenous injection which may have an adverse effect on the dog. The effectiveness of Zycortal Suspension may be reduced if potassium-sparing diuretics, such as spironolactone, are administered concurrently. Use Zycortal Suspension with caution in dogs with congestive heart disease, edema, severe renal disease or primary hepatic failure. Desoxycorticosterone pivalate may cause polyuria, polydipsia, increased blood volume, edema and cardiac enlargement. Excessive weight gain may indicate fluid retention secondary to sodium retention. The safety of desoxycorticosterone pivalate has not been established in breeding, pregnant and lactating dogs and dogs less than 6 months of age.
Contact your nearest emergency animal hospital
How can I store Zycortal Suspension for Dogs, 25 mg/ml, 4 ml Vial?
Store between 15-30°C. Do not freeze. Use within 120 days of first puncture.
Use as directed by your veterinarian.
Desoxycorticosterone Pivalate
