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Item No.
52291
Product Description
Vetsulin VetPen Cartridge, 2.7 ml (40 units per ml) (porcine insulin zinc suspension) is indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in dogs and cats with diabetes mellitus.
Vetsulin VetPen Cartridges should be used exclusively with VetPens (#50992) sold separately.
* This is a cold ship item.
What is Vetsulin VetPen, 10 x 2.7 ml Cartridges?
Vetsulin VetPen Cartridge, 2.7 ml (40 units per ml) (porcine insulin zinc suspension) is indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in dogs and cats with diabetes mellitus.
Who is Vetsulin VetPen, 10 x 2.7 ml Cartridges for?
Dogs and Cats
Why use Vetsulin VetPen, 10 x 2.7 ml Cartridges?
-Vetsulin VetPen Cartridges should be used exclusively with VetPens (#50992) and VetPen Needles 12 mm (29 g) (#50990) sold separately.
-Vetsulin is an ideal insulin choice for your canine and feline patients with diabetes.
-Vetsulin is the only FDA-approved insulin for use in diabetic dogs and cats in the USA.
-Vetsulin is indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in dogs and cats with diabetes mellitus.
How does Vetsulin VetPen, 10 x 2.7 ml Cartridges work?
Porcine insulin is similar in amino acid structure to canine insulin. Vetsulin is classified as an intermediate acting insulin. In dogs, Vetsulin has two peaks of activity following subcutaneous administration (the first at around 4 hours and the second at around 11 hours). The duration of activity varies between 14 and 24 hours. In cats, the peak activity following subcutaneous administration of Vetsulin occurs between 1.5 and 8 hours, and the duration of activity varies between 8 and 12 hours. The peak duration of activity and dose required to adequately control diabetic signs will vary from pet to pet.
Manufacturer:
Merck
Active Ingredients(s):
Vetsulin is a sterile aqueous zinc suspension of purified porcine insulin.
Each mL contains:
purified porcine insulin (35% amorphous and 65% crystalline) 40 IU
Zinc (as chloride) 0.08 mg
Sodium acetate trihydrate 1.36 mg
Sodium chloride 7.0 mg
Methylparaben (preservative) 1.0 mg
pH is adjusted with hydrochloric acid and/or sodium hydroxide.
How is Vetsulin VetPen, 10 x 2.7 ml Cartridges sold?
Sold as 10 x 2.7 ml (40 units per ml) cartridges for use exclusively with VetPens (#50992) and VetPen Needles 12 mm (29 g) (#50990) sold separately.
What are the side effects of Vetsulin VetPen, 10 x 2.7 ml Cartridges?
The most common side effect of insulin is low blood sugar (hypoglycemia), which may be serious and life threatening. It may cause harm to your heart or brain. Symptoms of serious low blood sugar may include shaking, sweating, fast heartbeat, and blurred vision. Other possible side effects include : allergic reactions, injection site reactions, lipodystrophy, pruritus, rash, edema and weight gain.
What special precautions are there?
Keep away from children and animals. Dogs and cats known to have a systemic allergy to pork or pork products should not be treated with Vetsulin. Vetsulin is contraindicated during periods of hypoglycemia. Avoid contact with eyes. In case of contact, immediately flush eyes with copious amounts of water for 15 minutes. Accidental injection may cause clinical hypoglycemia. In case of accidental injection, seek medical attention immediately. Exposure to product may induce a local or systemic allergic reaction in sensitized individuals. The safety and effectiveness of vetsulin in breeding, pregnant, and lactating dogs and cats has not been evaluated. The safety and effectiveness of Vetsulin in puppies and kittens has not been evaluated.
What to do if overdose?
Contact your nearest emergency animal hospital
How can I store Vetsulin VetPen, 10 x 2.7 ml Cartridges?
Store in an upright position under refrigeration at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. The loaded VetPen can be stored on its side. Use contents within 42 days of first puncture.
Overview
Use as directed by your veterinarian
Vetsulin VetPen Cartridges should be used exclusively with VetPens (#50992) and VetPen Needles 12 mm (29 g) (#50990) sold separately.
Prior to loading Vetsulin cartridges, shake the cartridge until a homogeneous, uniformly milky suspension is obtained. Clumps or white particles can form in insulin suspensions: do not use the product if visible clumps or white particles persist after shaking.
The detailed instructions for use provided with VetPen should be strictly followed.
The injection should be administered subcutaneously, 2 to 5 cm (3/4 to 2 in) from the dorsal midline, varying from behind the scapulae to the mid-lumbar region and alternating sides.
Dogs
The initial recommended vetsulin® dose is 0.5 IU insulin/kg body weight. Initially, this dose should be given once daily concurrently with, or right after a meal.
Twice daily therapy should be initiated if the duration of insulin action is determined to be inadequate. If twice daily treatment is initiated, the two doses should each be 25% less than the once daily dose required to attain an acceptable nadir. For example, if a dog receiving 20 units of vetsulin® once daily has an acceptable nadir but inadequate duration of activity, the vetsulin® dose should be changed to 15 units twice daily.
The veterinarian should re-evaluate the dog at appropriate intervals and adjust the dose based on clinical signs, urinalysis results, and glucose curve values until adequate glycemic control has been attained. Further adjustments in dosage may be necessary with changes in the dog’s diet, body weight, or concomitant medication, or if the dog develops concurrent infection, inflammation, neoplasia, or an additional endocrine or other medical disorder.
Cats
The initial recommended dose in cats is 1 to 2 IU per injection. The injections should be given twice daily at approximately 12 hour intervals. For cats fed twice daily, the injections should be given concurrently with, or right after each meal. For cats fed ad libitum, no change in feeding schedule is needed.
The veterinarian should re-evaluate the cat at appropriate intervals and adjust the dose based on clinical signs, urinalysis results, and glucose curve values until adequate glycemic control has been attained. Further adjustments in dosage may be necessary with changes in the cat’s diet, body weight, or concomitant medication, or if the cat develops concurrent infection, inflammation, neoplasia, or an additional endocrine or other medical disorder.
Main Ingredients
Vetsulin VetPen Cartridge 2.7 ml (40 units per ml) is for use with VetPens (#50992) and VetPen Needles 12 mm (29 g) (#50990) sold separately.
Vetsulin is a sterile aqueous zinc suspension of purified porcine insulin.
Each mL contains:
purified porcine insulin (35% amorphous and 65% crystalline) 40 IU
Zinc (as chloride) 0.08 mg
Sodium acetate trihydrate 1.36 mg
Sodium chloride 7.0 mg
Methylparaben (preservative) 1.0 mg
pH is adjusted with hydrochloric acid and/or sodium hydroxide.