Marquis antiprotozoal oral paste is used for the treatement of EPM (Equine Protozoal Myeloencephalitis). Each 127 gm tube will treat a 1200-pound horse for seven days (the usual course of treatment is 28 days). Marquis kills parasites at several life stages.
What is Marquis 127 gm tube?
Marquis (Ponazuril) Paste is used to treat Equine Protozoal Myeloencephalitis. The active ingredient is ponazuril, an anticoccidial compound with cidal activity against Sarcocystis neurona, the protozoal parasite that causes equine protozoal myeloencephalitis (EPM).
Who is Marquis 127 gm tube for?
Horses
Why use Marquis 127 gm tube?
To protect against sarcocystis neurona, which causes EPM
How does Marquis 127 gm tube work?
Active ingredient Ponazuril acts against the parasite to kill it
Boehringer Ingelheim
15% w/w ponazuril
How is Marquis 127 gm tube sold?
Sold as individual 127 gram tube
What are the side effects of Marquis 127 gm tube?
Blisters on the nose and mouth, skin rash or hives for up to 18 days, loose stools throughout the treatment period, mild colic and seizures have been observed in some case of horses treated with Marquis.
What special precautions are there?
The safe use of this product in horses used for breeding purposes, during pregnancy or in lactating mares, has not been evaluated.
Contact your nearest emergency animal hospital.
How can I store Marquis 127 gm tube?
Store at Controlled Room Temperature 15-30° C (59-86° F).
Marquis should effectively clear the horse of S. neurona, but may have no effect on irreparable, pre-existing CNS damage caused by the protozoal parasite prior to treatment.
Marquis® (15% w/w ponazuril) Antiprotozoal Oral Paste is supplied in ready-to-use syringes 127 grams of paste. Each gram of paste contains 150 mg of ponazuril (15% w/w). Marquis (ponazuril) is designed to be delivered as an orally administered paste.
DOSAGE: Marquis (15% w/w ponazuril) is to be used at a dose of 5 mg/kg (2.27 mg/lb) body weight once daily for a period of 28 days. * Sold as individual 127 gm tube. Customer will need to purchase 4 tubes if they want full course treatment.
Administering Marquis (ponazuril) to the horse:
Step 1. Remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. Return end cap to tip of paste syringe.
Step 2. Determine weight of horse and insure the horse's mouth contains no feed.
Step 3. To measure dose, dosage ring collar and barrel collar should be flush. Hold plunger and rotate dosage ring with the other hand to the weight of the horse.
Step 4. Remove end cap from tip of syringe barrel.
Step 5. The selected dose of paste should be deposited onto the back and top of the horse's tongue. Introduce tip of paste syringe into the side of the horse's mouth at the space between the front (incisor) and back (molar) teeth. Deposit paste on the horse's tongue by depressing the plunger of the syringe as far as the dose ring permits. Remove tip of syringe from horse's mouth.
Step 6. To aid swallowing of paste, immediately raise horse's head for a few seconds after dosing.
Step 7. Clean the tip of the syringe with a clean disposable towel and return end cap to tip of syringe barrel.
Step 8. For the next daily dose, repeat steps 1-7.
NOTE: At the end of the prescribed treatment period, partially used syringes should be discarded.
Ponazuril 1,3,5-Triazine-2,4,6(1H, 3H, 5H)-trione,1-methyl-3-[3-methyl-4-[4-[(trifluoromethyl)sulfonyl] phenoxy]phenyl]-(9CI)
