Phenylbutazone Injection is for the relief of lameness due to arthritis and musculoskeletal conditions in horses.
What is Bute Injectable 200 mg/ml, 100 ml?
Phenylbutazone is a non-steroidal anti-inflammatory drug. It also has analgesic (pain relief) and antipyretic (fever-reducing) effects and is indicated for the treatment of a wide range of musculoskeletal disorders, including muscular sprain and strain, muscular overuse (including both muscular damage and strain/damage of the tendons attaching muscles to bone), tendonitis, acute joint injury/strain/sprain, and arthritic conditions.
Who is Bute Injectable 200 mg/ml, 100 ml for?
Horses
Why use Bute Injectable 200 mg/ml, 100 ml?
-For relief of inflammatory conditions associated with the musculoskeletal system in horse
-Control pain from injuries, infections, laminitis, or virtually any other source of pain
How does Bute Injectable 200 mg/ml, 100 ml work?
The analgesic effect is related mainly to the compound's anti-inflammatory properties.
VetOne
Contains 200 mg phenylbutazone, 1.5% benzyl alcohol and purified water per ml.
How is Bute Injectable 200 mg/ml, 100 ml sold?
100 ml Vial, 200 Mg/ml (1 G/5 Ml)
What are the side effects of Bute Injectable 200 mg/ml, 100 ml?
Stop medication at the first sign of gastrointestinal upset, jaundice, or blood dyscrasia. Authenticated cases of agranulocytosis associated with the drug have occurred in man; fatal reactions, although rare, have been reported in dogs after long-term therapy. To guard against this possibility, conduct routine blood counts at weekly intervals during the early phase of therapy and at intervals of two weeks thereafter. Any significant fall in the total white count, relative decrease in granulocytes, or black or tarry stools, should be regarded as a signal for immediate cessation of therapy and institution of appropriate countermeasures.
What special precautions are there?
Parenteral injections should be made intravenously only; do not inject subcutaneously or intramuscularly. Use with caution in patients who have a history of drug allergy.
Contact your nearest emergency animal clinic.
How can I store Bute Injectable 200 mg/ml, 100 ml?
Store In A Refrigerator Between 2°c And 8°c (36°f And 46°f).
In the treatment of inflammatory conditions associated with infections, specific anti-infective therapy is required.
Intravenously
1 to 2 g per 1,000 lbs of body weight (5 to 10 mL/1,000 lbs) daily. Injection should be given slowly and with care. Limit intravenous administration to a maximum of 5 successive days, which may be followed by oral phenylbutazone dosage forms.
Guidelines To Succesful Therapy
1. Use a relatively high dose for the first 48 hours, then reduce gradually to a maintenance dose. Maintain lowest dose capable of producing desired clinical response.
2. Response to phenylbutazone therapy is prompt, usually occurring within 24 hours. If no significant clinical response is evident after 5 days, reevaluate diagnosis and therapeutic approach.
3. In animals, phenylbutazone is largely metabolized in 8 hours. It is recommended that a third of the daily dose be administered at 8 hour intervals. Reduce dosage as symptoms regress. In some cases, treatment may be given only when symptoms appear with no need for continuous medication. If long-term therapy is planned, oral administration is suggested.
4. Many chronic conditions will respond to phenylbutazone therapy, but discontinuance of treatment may result in recurrence of symptoms.
Injection: For Horses Only: 100 Ml Vials, 200 Mg/ml (1 G/5 Ml)
Each mL contains 200 mg of phenylbutazone, 10.45 mg of benzyl alcohol as preservative, sodium hydroxide to adjust pH to 9.5 to 10.0, and water for injection, Q.S.
