Banamine Injectable is a sterile solution of flunixin meglumine used for alleviation of pain and inflammation associated with colic and musculoskeletal disorders in horses. Banamine Injectable is now approved for cattle in the U.S.
What is Banamine Injectable?
BANAMINE Injectable Solution is recommended for the relief of pain in horses, reduce inflammation associated with musculoskeletal disorders and for the alleviation of visceral pain associated with colic in horses.
In Cattle, Banamine is used the control of pyrexia (fever) associated with bovine respiratory disease and endotoxemia, and for the control of inflammation in endotoxemia.
Who is Banamine Injectable for?
Horse & Cattle
Why use Banamine Injectable?
- Treat pain & lameness in horses
- Reduce inflammation caused by musculoskeletal disorders
- Fast acting relief for horses and cattle
How does Banamine Injectable work?
Flunixin meglumine, the main ingredient in Banamine Injectable Solution (flunixin meglumine), is used to relieve pain and inflammation in horses and cattle and for its antipyretic properties. Banamine injectable is a part of the non-steroidal anti-inflammatory class of drugs (NSAIDs).
Merck Animal Health.
FLUNIXIN MEGLUMINE
How is Banamine Injectable sold?
100ml
250ml
What are the side effects of Banamine Injectable?
In horse, isolated reports of local reactions following intramuscular injection, particularly in the neck, have been received. These include localized swelling, sweating, induration, and stiffness. In rare instances in horses, fatal or nonfatal clostridial infections or other infections have been reported in association with intramuscular use of flunixin meglumine. In horses and cattle, rare instances of anaphylactic-like reactions, some of which have been fatal, have been reported, primarily following intravenous use.
What special precautions are there?
Horse: The effect of BANAMINE Injectable Solution on pregnancy has not been determined. Studies to determine activity of BANAMINE Injectable Solution when administered concomitantly with other drugs have not been conducted. Drug compatibility should be monitored closely in patients requiring adjunctive therapy.
Cattle: Do not use in bulls intended for breeding, as reproductive effects of Banamine Injectable Solution in these classes of cattle have not been investigated. NSAIDs are known to have potential effects on both parturition (See Contraindications) and the estrous cycle. There may be a delay in the onset of estrus if flunixin is administered during the prostaglandin phase of the estrous cycle. NSAIDs are known to have the potential to delay parturition through a tocolytic effect. The use of NSAIDs in the immediate post-partum period may interfere with uterine involution and expulsion of fetal membranes. Cows should be monitored carefully for placental retention if Banamine Injectable Solution is used within 24 hours after parturition.
Contact your nearest animal emergency hospital. You may also contact Merck Animal Health Pharmacovigilance: Livestock Technical Services, 800-211-3573
How can I store Banamine Injectable?
Store between 2° and 30°C (36° and 86°F).
Always read package inserts and directions.
Horse: BANAMINE Injectable Solution is recommended for the alleviation of inflammation and pain associated with musculoskeletal disorders in the horse. It is also recommended for the alleviation of visceral pain associated with colic in the horse.
Horse: The recommended dose for musculoskeletal disorders is 0.5 mg per pound (1 mL/100 lbs) of body weight once daily. Treatment may be given by intravenous or intramuscular injection and repeated for up to 5 days. Studies show onset of activity is within 2 hours. Peak response occurs between 12 and 16 hours and duration of activity is 24-36 hours.
The recommended dose for the alleviation of pain associated with equine colic is 0.5 mg per pound of body weight. Intravenous administration is recommended for prompt relief. Clinical studies show pain is alleviated in less than 15 minutes in many cases. Treatment may be repeated when signs of colic recur. During clinical studies approximately 10% of the horses required one or two additional treatments. The cause of colic should be determined and treated with concomitant therapy.
Cattle: BANAMINE Injectable Solution is indicated for the control of pyrexia associated with bovine respiratory disease, endotoxemia and acute bovine mastitis. BANAMINE Injectable Solution is also indicated for the control of inflammation in endotoxemia.
Cattle: The recommended dose for control of pyrexia associated with bovine respiratory disease and endotoxemia and control of inflammation in endotoxemia, is 1.1 to 2.2 mg/kg (0.5 to 1 mg/lb; 1 to 2 mL per 100 lbs) of body weight given by slow intravenous administration either once a day as a single dose or divided into two doses administered at 12-hour intervals for up to 3 days. The total daily dose should not exceed 2.2 mg/kg (1.0 mg/lb) of body weight. Avoid rapid intravenous administration of the drug.
The recommended dose for acute bovine mastitis is 2.2 mg/kg (1 mg/lb; 2 mL per 100 lbs) of body weight given once by intravenous administration.
Each milliliter of BANAMINE Injectable Solution contains flunixin meglumine equivalent to 50 mg flunixin, 0.1 mg edetate disodium, 2.5 mg sodium formaldehyde sulfoxylate, 4.0 mg diethanolamine, 207.2 mg propylene glycol; 5.0 mg phenol as preservative, hydrochloric acid, water for injection qs.
